ScreenChip Cartridge – box of 10

Quick and Easy

 

The ScreenChip Cartridge, used with the ScreenChip System is a microfluidic device designed for rapid, accurate data collection from C. elegans and related nematodes. Real-time data is recorded using a pocket-sized amplifier and streamed to a PC or Mac via Bluetooth.

 

Just by sliding it into place, each disposable cartridge effortlessly makes a robust connection to the ScreenChip Dock. The ScreenChip moves worms one by one from an Eppendorf tube and into a recording chamber which detects electrical signals from the pharyngeal pumping of the worm. Each cartridge is capable of recording up to 50 worms per chip, or one to two days of use.

Available in packages of 10. The variety pack includes 2 x SC10, 2 x SC20, 2 x SC30, 2 x SC40, and 2 x SC 60.

 

Choosing the right Screenchip:

Chip Name C. elegans age Channel Height Smallest Point
ScreenChip 10 L1 10 μm 10 μm
ScreenChip 20 L2 16 μm 16 μm
ScreenChip 30 L4 40 μm 30 μm
ScreenChip 40 1st to 5th day adults 60 μm 40 μm
ScreenChip 60 5th day adults and up 90 μm 60 μm
ScreenChip Variety Pack
(2 of each size)
L1 to older adults n/a n/a
Custom ScreenChip Variety Pack L1 to older adults n/a n/a

 

Product Specifications

  • Species: C. elegans, C. briggsae, P. pacificus
  • Ages: See size table
  • Throughput: up to 50 worms per chip
  • Weight (g): 16.7
  • Dimensions (mm): 31.75 x 79.4 x 10.2
    Electrode Composition: Indium tin oxide (ITO)
    Cartridge Composition:
    - Upper: Polydimethylsiloxane (PDMS)
    - Lower: Glass
  • Port Size (mm): 1.5

ScreenChip Cartridge – box of 10

€ 514,95Price
Choose an Option
    • Montmorency tart cherry (Prunus cerasus L.) acts as a calorie restriction mimetic that increases intestinal fat and lifespan in Caenorhabditis elegans. Davidvan de Klashorst, Ambervan den Elzen, Jasper Weeteling, Michael Roberts, Terun Desai, Lindsay Bottoms, Samantha Hughes. Journal of Functional Foods. Volume 68, May 2020, 103890.
       
    • Ahr-bacterial diet interaction modulates aging and associated pathologies in C. elegans. Vanessa Brinkmann, Alfonso Schiavi, Anjumara Shaik, Daniel R. Puchta, Natascia Ventura. bioRxiv. May 19, 2020.
       
    • Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans. Chaolie Huang, Sara Wagner-Valladolid, Amberley D Stephens, Raimund Jung, Chetan Poudel, Tessa Sinnige, Marie C Lechler, Nicole Schlörit, Meng Lu, Romain F Laine, Claire H Michel, Michele Vendruscolo, Clemens F Kaminski, Gabriele S Kaminski Schierle, Della C David. elife. May 3, 2019
       
    • Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized Caenorhabditis elegans. Bangfu Zhu, Jennifer C. H. Mak, Andrew P. Morris, Anthony G. Marson, Jeff W. Barclay, Graeme J. Sills, Alan Morgan. Epilepsia. 2020;61:810–82
       
    • Statins Induce a DAF-16/Foxo-dependent Longevity Phenotype via JNK-1 through Mevalonate Depletion in C. elegans. Andreas Jahn, Bo Scherer, Gerhard Fritz, Sebastian Honnen. Aging and Disease. Volume 11, Number 1; 60-72, February 2020.
    • Resolving a contradiction: full gene deletion of kqt-3 by CRISPR does not lead to pharyngeal pumping defects. R. Baur, B. Nebenfuehr, A. Golden. https://www.micropublication.org/journals/biology/micropub-biology-000137/

    • The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes. C. Ménez, M. Alberich, E. Courtot, F. Guegnard, A. Blanchard, H. Aguilaniu, A. Lespine. https://doi.org/10.1371/ journal.ppat.1007598
       
    • Electrophysiological measures of aging pharynx function in C. elegans reveal enhanced organ functionality in older, long-lived mutants. J. Russell, N. Burnaevskiy, B. Ma, M. Mailig, F. Faust, M. Crane, M. Kaeberlein, A. Mendenhall. The Journals of Gerontology: Series A, Nov. 2017.
       
    • Tool-Driven Advances in Neuropeptide Research from a Nematode Parasite Perspective. CJ McCoy, LE Atkinson, E Robb, NJ Marks, AG Maule, A Mousley. Trends Parasitol. 2017 Dec;33(12):986-1002. doi: 10.1016/j.pt.2017.08.009. Epub 2017 Oct 3.
       
    • Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. K. Hueffer, S. Khatri, S. Rideout, M. Harris, R. Papke, C. Stokes & M. Schulte. Nature Scientific Reports 7, Article number: 12818 (2017)
       
    • Distinct unfolded protein responses mitigate or mediate effects of nonlethal deprivation of C. elegans sleep in different tissues.  J. Sanders, M. Scholz, I, Merutka and D. Biron. BMC Biology 2017 15:67.

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